PICALM Polyclonal Antibody

• Background:

  This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t (10;11) (p13; q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a PICALM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PICALM, CALM, CLTH, LAP

• Gene ID:

  8301

• Swiss Prot:

  Q13492

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human PICALM

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:1000-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  14kDa

• Observed Molecular Weight:

  14kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG