CFHR5 Polyclonal Antibody

• Background :

  This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS) .

• Description :

  This is a CFHR5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CFHR5, CFHL5, CFHR5D, FHR-5, FHR5

• Gene ID :

  81494

• Swiss Prot :

  Q9BXR6

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human CFHR5

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  57kDa/61kDa/63kDa/66kDa

• Observed Molecular Weight :

  72kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG