Products for Research Use Only

SPSB1 Polyclonal Antibody

CAT: 0866-RD87214A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87214A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Negatively regulates nitric oxide (NO production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2. Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5.
Description
This is a SPSB1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SPSB1, SSB-1, SSB1
Gene ID
80176
Swiss Prot
Q96BD6
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human SPSB1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
236kDa/266kDa/278kDa
Observed Molecular Weight
280kDa
Host or Source
Rabbit
Isotype
IgG