Products for Research Use Only

PDK3 Polyclonal Antibody

CAT: 0866-RD86879A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD86879A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2) . It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a PDK3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PDK3, CMTX6, GS1-358P8.4
Gene ID
5165
Swiss Prot
Q15120
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PDK3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
27kDa
Observed Molecular Weight
27kDa
Host or Source
Rabbit
Isotype
IgG