MLH3 Polyclonal Antibody

• Background:

  This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7) . Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

• Description:

  This is a MLH3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MLH3, HNPCC7

• Gene ID:

  27030

• Swiss Prot:

  Q9UHC1

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human MLH3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  30kDa

• Observed Molecular Weight:

  30kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG