BAG3 Polyclonal Antibody

• Background:

  Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

• Description:

  This is a BAG3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BAG family molecular chaperone regulator 3 , BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, BIS

• Swiss Prot:

  O95817

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant Human BAG3 protein expressed by E.coli

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.4mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  12 kDa

• Observed Molecular Weight:

  14 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG