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GPS2 Polyclonal Antibody

CAT: 0866-RD89587A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89587A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Description
This is a GPS2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GPS2, AMF-1
Gene ID
56310
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of mouse GPS2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IP
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IP 1:20-1:50
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
51kDa
Observed Molecular Weight
55kDa
Host or Source
Rabbit
Isotype
IgG

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