POMC Polyclonal Antibody

CAT: 0866-RD89536A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD89536A-01Size:60 μL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
Description
This is a POMC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
POMC, ACTH, CLIP, LPH, MSH, NPP, POC
Gene ID
5443
Swiss Prot
P01189
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human POMC
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
50kDa
Observed Molecular Weight
50kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RDSA65524POMC Rabbit mAb
RDR-POMC-Eq-01Equine Pro-opiomelanocortin (POMC)
RD-POMC-Eq-01Equine Pro-opiomelanocortin (POMC)
RD-POMC-Hu-48TestsHuman Proopiomelanocortin (POMC) ELISA Kit
RDR-POMC-Hu-48TestsHuman Proopiomelanocortin (POMC) ELISA Kit
RDR-POMC-Mu-96TestsMouse Proopiomelanocortin (POMC) ELISA Kit
RD-POMC-Ra-48TestsRat Proopiomelanocortin (POMC) ELISA Kit
RDR-POMC-Hu-96TestsHuman Proopiomelanocortin (POMC) ELISA Kit
RD-POMC-Mu-01Mouse Proopiomelanocortin (POMC) ELISA Kit
RDR-POMC-Hu-01Human Proopiomelanocortin (POMC) ELISA Kit

Alternative Products

CatalogName
MBS8571595-01POMC Polyclonal Antibody
BS77022POMC polyclonal antibody
CAU26166-01Proopiomelanocortin (POMC) Polyclonal Antibody
MBS2126715-01Polyclonal Antibody to Proopiomelanocortin (POMC)

Popular Products