PRMT6 Polyclonal Antibody

CAT: 0866-RD89500A-01Size: 120 μLDry Ice: NoHazardous: No
CAT#:0866-RD89500A-01Size:120 μL
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Background
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Description
This is a PRMT6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PRMT6, HRMT1L6
Gene ID
55170
Swiss Prot
Q96LA8
Reactivity
Human
Immunogen
Recombinant fusion protein of human PRMT6
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:1000, IF 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
147kDa
Observed Molecular Weight
147KDa
Host or Source
Rabbit
Isotype
IgG

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