ATG4D Polyclonal Antibody

• Background:

  Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.

• Description:

  This is a ATG4D Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ATG4D, APG4-D, APG4D, AUTL4, cysteine protease ATG4D

• Gene ID:

  84971

• Swiss Prot:

  Q86TL0

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human ATG4D

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  26kDa/31kDa/35kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG