Products for Research Use Only

STIM1 Polyclonal Antibody

CAT: 0866-RD89436A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89436A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs) . It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants.
Description
This is a STIM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
STIM1, D11S4896E, GOK, IMD10, STRMK, TAM, TAM1, stromal interaction molecule 1
Gene ID
6786
Swiss Prot
Q13586
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human STIM1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IP
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
IHC 1:50-1:100, IP 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
76kDa/79kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG