Bcdin3d Polyclonal Antibody

• Background :

  O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA (His, acting as a capping enzyme by protecting tRNA (His from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.

• Description :

  This is a Bcdin3d Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  AV138748, 4930556P03Rik

• Gene ID :

  75284

• Swiss Prot :

  Q91YP1

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein of mouse Bcdin3d

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000, IF 1:50-1:200

• Buffer :

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  125kDa

• Observed Molecular Weight :

  126KDa

• Host or Source :

  Rabbit

• Isotype :

  IgG