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SCAF8 Polyclonal Antibody

CAT: 0866-RD89195A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89195A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Anti-terminator protein required to prevent early mRNA termination during transcription. Together with SCAF4, acts by suppressing the use of early, alternative poly (A sites, thereby preventing the accumulation of non-functional truncated proteins. Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD of the largest RNA polymerase II subunit (POLR2A, and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation. Independently of SCAF4, also acts as a positive regulator of transcript elongation.
Description
This is a SCAF8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SCAF8, RBM16
Gene ID
22828
Swiss Prot
Q9UPN6
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SCAF8
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
120kDa
Observed Molecular Weight
140KDa
Host or Source
Rabbit
Isotype
IgG

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