IL24 Polyclonal Antibody

• Background:

  This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

• Description:

  This is a IL24 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  IL24, C49A, FISP, IL10B, MDA7, MOB5, ST16

• Gene ID:

  11009

• Swiss Prot:

  Q13007

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human IL24

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  56kDa/57kDa/58kDa

• Observed Molecular Weight:

  58KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG