RRAGA Polyclonal Antibody

CAT: 0866-RD88096A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD88096A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.
Description
This is a RRAGA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
RRAGA, FIP-1, FIP1, RAGA
Gene ID
10670
Swiss Prot
Q7L523
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human RRAGA
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35kDa
Observed Molecular Weight
36KDa
Host or Source
Rabbit
Isotype
IgG

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