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RBL2 Polyclonal Antibody

CAT: 0866-RD87691A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87691A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Description
This is a RBL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
RBL2, P130, Rb2
Gene ID
5934
Swiss Prot
Q08999
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human RBL2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IF 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
122kDa
Host or Source
Rabbit
Isotype
IgG

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