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KCNJ3 Polyclonal Antibody

CAT: 0866-RD87471A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87471A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins.
Description
This is a KCNJ3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
KCNJ3, GIRK1, KGA, KIR3.1
Gene ID
3760
Swiss Prot
P48549
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human KCNJ3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
16kDa/24kDa
Observed Molecular Weight
25kDa
Host or Source
Rabbit
Isotype
IgG

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