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BCL2A1 Polyclonal Antibody

CAT: 0866-RD87101A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87101A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a BCL2A1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BCL2A1, ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1
Gene ID
597
Swiss Prot
Q16548
Reactivity
Human
Immunogen
A synthetic peptide of human BCL2A1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33kDa/46kDa
Observed Molecular Weight
50kDa
Host or Source
Rabbit
Isotype
IgG

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