OCT4 Polyclonal Antibody

• Background:

  This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

• Description:

  This is a 45934 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4

• Gene ID:

  5460

• Swiss Prot:

  Q01860

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide of human OCT4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  46kDa/48kDa

• Observed Molecular Weight:

  47kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG