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GTPase Kras Polyclonal Antibody

CAT: 0866-RD86687A-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0866-RD86687A-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon (PMID: 12778136) . KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP) -binding protein and is widely expressed in most human cells. Like other members of the Ras family, the KRAS protein is a GTPase, and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687) . KRAS mutations have been found in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.
Description
This is a GTPase Kras Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
KRAS, KRAS2, RASK2, GTPase Kras, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, GTPase Kras
Gene ID
3845
Swiss Prot
P01116
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human KRAS protein expressed by E.coli.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
2.5mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH 7.4
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa
Observed Molecular Weight
56 kDa
Host or Source
Rabbit
Isotype
IgG

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