CST3 Polyclonal Antibody

• Background:

  Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.

• Description:

  This is a CST3 Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  AD8, Amyloid angiopathy and cerebral hemorrhage, ARMD11, CST3 protein, Cystatin 3, CystatinC, Epididymis secretory protein Li 2, bA218C14.4, Gamma trace, HCCAA, HEL S 2, Neuroendocrine basic polypeptide, Post gamma globulin

• Swiss Prot:

  P01034

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant Human CST3 protein expressed by E.coli

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000, IHC 1:250-1:500

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  25 kDa

• Observed Molecular Weight:

  26 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG