UCP3 Polyclonal Antibody

CAT: 0866-RD90201A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD90201A-01Size:60 μL
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Background
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP) . UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.
Description
This is a UCP3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
UCP3, SLC25A9
Gene ID
7352
Swiss Prot
P55916
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human UCP3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
21kDa
Observed Molecular Weight
32KDa
Host or Source
Rabbit
Isotype
IgG

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