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APP Polyclonal Antibody

CAT: 0866-RD89308A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89308A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy) . Multiple transcript variants encoding several different isoforms have been found for this gene.
Description
This is a APP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4, APP, Aβ42, preA4
Gene ID
351
Swiss Prot
P05067
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human APP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
113kDa
Observed Molecular Weight
90-115KDa
Host or Source
Rabbit
Isotype
IgG

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