ATP6V0A1 Polyclonal Antibody

• Background:

  This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a ATP6V0A1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ATP6V0A1, ATP6N1, ATP6N1A, Stv1, VPP1, Vph1, a1

• Gene ID:

  535

• Swiss Prot:

  Q93050

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human ATP6V0A1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  IF 1:50-1:200

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  17kDa/22kDa

• Observed Molecular Weight:

  22kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG