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Bcl10 Polyclonal Antibody

CAT: 0866-RD87103A-01Size: 120 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87103A-01Size:120 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
Description
This is a Bcl10 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BCL10, CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
Gene ID
8915
Swiss Prot
O95999
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human Bcl10
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40kDa/43kDa
Observed Molecular Weight
46kDa
Host or Source
Rabbit
Isotype
IgG

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