GPBAR1 Polyclonal Antibody

CAT: 0866-RD90276A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD90276A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
Description
This is a GPBAR1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BG37, TGR5, M-BAR, GPCR19, GPR131
Gene ID
151306
Swiss Prot
Q8TDU6
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human GPBAR1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IF 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35kDa/53kDa/59kDa/60kDa/81kDa/91kDa/93kDa
Observed Molecular Weight
140KDa
Host or Source
Rabbit
Isotype
IgG

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