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HN1 Polyclonal Antibody

CAT: 0866-RD88477A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD88477A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation.
Description
This is a HN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
JPT1, ARM2, HN1, HN1A
Gene ID
51155
Swiss Prot
Q9UK76
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human HN1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22kDa
Observed Molecular Weight
23kDa
Host or Source
Rabbit
Isotype
IgG

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