MDC1 Polyclonal Antibody

CAT: 0866-RD87512A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD87512A-01Size:60 μL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Description
This is a MDC1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MDC1, NFBD1
Gene ID
9656
Swiss Prot
Q14676
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human MDC1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
25kDa
Observed Molecular Weight
29kDa
Host or Source
Rabbit
Isotype
IgG

Popular Products