TNF-α Polyclonal Antibody

• Background:

  This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

• Description:

  This is a TNF-α Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  TNF, DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F, TNF alpha

• Gene ID:

  7124

• Swiss Prot:

  P01375

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human TNF

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  564kDa/565kDa

• Observed Molecular Weight:

  564KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG