TYK2 Polyclonal Antibody

• Background:

  This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

• Description:

  This is a TYK2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  TYK2, IMD35, JTK1

• Gene ID:

  7297

• Swiss Prot:

  P29597

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human TYK2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IF 1:50-1:200

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  25kDa

• Observed Molecular Weight:

  17-110kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG