NRAS Polyclonal Antibody

CAT: 0866-RD89809A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD89809A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Description
This is a NRAS Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NRAS, ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6
Gene ID
4893
Swiss Prot
P01111
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human NRAS
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IF 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38kDa/46kDa
Observed Molecular Weight
47kDa
Host or Source
Rabbit
Isotype
IgG

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