NRAS Polyclonal Antibody

• Background :

  This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

• Description :

  This is a NRAS Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  NRAS, ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6

• Gene ID :

  4893

• Swiss Prot :

  P01111

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human NRAS

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000, IF 1:50-1:200

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  38kDa/46kDa

• Observed Molecular Weight :

  47kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG