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NOD2 Polyclonal Antibody

CAT: 0866-RD88439A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD88439A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs) . The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Description
This is a NOD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NOD2, ACUG, BLAU, BLAUS, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1, YAOS
Gene ID
64127
Swiss Prot
Q9HC29
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human NOD2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
85kDa/90kDa/91kDa
Observed Molecular Weight
120KDa
Host or Source
Rabbit
Isotype
IgG

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