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IL18 Polyclonal Antibody

CAT: 0866-RD90268A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD90268A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-18 (L-18) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS) . After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Description
This is a IL18 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Ig, Il-, Igif, Il-18
Gene ID
16173
Swiss Prot
P70380
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of mouse IL18
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
10kDa
Observed Molecular Weight
11KDa
Host or Source
Rabbit
Isotype
IgG

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