Products for Research Use Only
RegisterLogin

Lenvatinib (Standard)

CAT: 0804-HY-10981R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-10981R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Lenvatinib (Standard) is the analytical standard of Lenvatinib. This product is intended for research and analytical applications. Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2].
CAS Number
417716-92-8
Product Name Alternative
E7080 (Standard)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Kit; FGFR; PDGFR; Reference Standards; RET; VEGFR
Type
Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lenvatinib-standard.html
Purity
99.77
Smiles
O=C(N)C1=C(C=C2N=CC=C(C2=C1)OC3=CC=C(C(Cl)=C3)NC(NC4CC4)=O)OC
Molecular Formula
C21H19ClN4O4
Molecular Weight
426.85
Precautions
H302, H315, H319, H335
References & Citations
[1]Kudo M, et al. Lenvatinib versus Bay 43-9006 in first-line treatment of patients with unresectable hepatocellularcarcinoma: a randomised phase 3 non-inferiority trial. Lancet. 2018 Mar 24;391 (10126) :1163-1173.|[2]Suyama K, et al. Lenvatinib: A Promising Molecular Targeted Agent for Multiple Cancers. Cancer Control. 2018 Jan-Dec;25 (1) :1073274818789361.|[3]Matsui J, et al. E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int J Cancer. 2008, 122 (3), 664-671.|[4]Matsui J, et al. Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase. Clin Cancer Res. 2008, 14 (17),545.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

Related Products

CatalogName
HY-10981AR-01Lenvatinib (mesylate) (Standard)
HY-W073260RLenvatinib impurity 1 (Standard)
HY-133980AR-01O-Demethyl Lenvatinib (hydrochloride) (Standard)
HY-10981-01Lenvatinib
HY-10981S1-01Lenvatinib-d5
HY-10981A-01Lenvatinib (mesylate)
HY-10981S-01Lenvatinib-d4
HY-W073260-01Lenvatinib impurity 1
HY-133980O-Demethyl Lenvatinib
HY-135742Lenvatinib N-oxide

Alternative Products

CatalogName
abx282895-01Lenvatinib

Popular Products