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Anti-MC4 | Metacaspase-4

CAT: 0451-AS19 4318Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0451-AS19 4318Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MC4 (Metacaspase-4) is a cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Plays a positive regulatory role in biotic and abiotic stress-induced programmed cell death. Alternative names: AtMCP2d, Metacaspase 2d
CAS Number
9007-83-4
HS Code
38221900
Gene ID
844272
UniProt
O64517
Host
Rabbit
Reactivity
Arabidopsis thaliana
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Immunogen
KLH-conjugated peptide derived from Arabidopsis thaliana MC4, UniProt: O64517, TAIR: At1g79340
Clonality
Polyclonal
Applications
Western blot (WB)
Field of Research
Wounding
Dilution
1 : 1000 (WB)
Purity
Immunogen affinity purified serum in PBS pH 7.4.
Format
Lyophilized
Reconstitution
For reconstitution add 50 µl, of sterile water
Molecular Weight
45.5 kDa
Precautions
Full-length MC4 (zMC4) disappears upon wounding. Accumulation of specific lower weight bands of active MC4 subunits, p20) is not detected with this antibody.
References & Citations
To be added when available, antibody released in November 2020.
Storage Conditions
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Prediction Reactivity
Raphanus sativus, Noccaea caerulescensSpecies of your interest not listed? Contact us

UniProtKB · O64517

Metacaspase-4

MCA4_ARATH · Arabidopsis thaliana

View on UniProt ↗
Primary accession
O64517
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AMC4
Protein existence
1: Evidence at protein level
Organism
Arabidopsis thaliana (Mouse-ear cress)
Taxonomy ID
3702
Alternative names
AtMC4
EC number
3.4.22.-
Processing
—
Secondary accessions
Q7XBI1
Protein keywords

Technical term

3D-structureReference proteome

PTM

Autocatalytic cleavageS-nitrosylation

Cellular component

Cytoplasm

Molecular function

HydrolaseProteaseThiol protease

Biological process

Plant defense
Product Datasheet
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