Anti-FtsH2 + FtsH8 | ATP-dependent zinc metalloprotease FtsH

• Background:

  FtsHbelong to a family of ATP dependent peptidases. Localized in a chloroplast are following isoforms: FTSH1 (synonymes AAA, FTSH, FTSH Protease 1), Ftsh2 (VAR2, VARIEGATED 2), FtsH5 (VAR1, VARIEGATED 1), FtsH6 (FTSH PROTEASE 6), FtsH7, FtsH8. FtsH9. Localized in mitochondria are following isoforms: FtsH3, FtsH4, FtsH10, FtsH11.FtsH2 (VAR2)is a component of the ATP-dependent zinc metallopeptidase. It is involved in the thylakoids biogenesis and in the repair of damaged D1 subunit of photosystem II, a process that protects against cell death under high light conditions. VAR1 transcript and protein levels increase with light intensity and it forms a complex with VAR1. Mutants show a variegated phenotype, which decreases during development.

• Host:

  Rabbit

• Reactivity:

  Arabidopsis thaliana,Nicotiana tabacum,Spinacia oleracea

• Not reactive in:

  Chlamydomonas reinhardtii

• Immunogen:

  RecombinantArabidopsis thalianaFtsH2, UniProt:O80860; TAIR:At2g30950

• Clonality:

  Polyclonal

• Applications:

  Western blot (WB)

• Dilution:

  1: 5000 (WB)

• Purity:

  Serum

• Format:

  Lyophilized

• Molecular Weight:

  65.6 kD (Arabidopsis thaliana)

• Precautions:

  Both FtsH2 (VAR2) and FtsH8 share high degree of homology therefore this antibody recognizes both proteins

• References & Citations:

  Zhaoet al. (2024). Psb28 protein is indispensable for stable accumulation of PSII core complexes in Arabidopsis.Plant J. 2024 May 26. doi: 10.1111/tpj.16844.

• Storage Conditions:

  Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

• CAS Number:

  9007-83-4