Anti-Abeta (1-42) | Amyloid-beta peptide 1-42

• Background:

  Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates ofamyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor proteinP05067

• Host:

  Chicken

• Reactivity:

  Human

• Not reactive in:

  No confirmed exceptions from predicted reactivity are currently known

• Immunogen:

  Synthetic peptide chosen from human Abeta (1-42) protein, Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A

• Clonality:

  Polyclonal

• Applications:

  Dot Blot (Dot), ELISA (ELISA)

• Dilution:

  1 : 1000 (Dot), 1 : 500 (ELISA)

• Purity:

  Purified total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.

• Format:

  Liquid

• Molecular Weight:

  4.5 kDa

• Precautions:

  The antibody can detect Abeta(1-42), but does not react with Abeta(1-28) Abeta(1-20) or Abeta(1-17)

• Storage Conditions:

  Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

• CAS Number:

  9007-83-4