MTHFD1 Polyclonal Antibody

• Background:

  This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

• Description:

  This is a MTHFD1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MTHFD1, MTHFC, MTHFD

• Gene ID:

  4522

• Swiss Prot:

  P11586

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human MTHFD1 (NP_005947.3) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:200-1:2000 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  101 kDa

• Observed Molecular Weight:

  115 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG