MTHFD1 Polyclonal Antibody

CAT: 0866-RD85225A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD85225A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
Description
This is a MTHFD1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MTHFD1, MTHFC, MTHFD
Gene ID
4522
Swiss Prot
P11586
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MTHFD1 (NP_005947.3) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:200-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
101 kDa
Observed Molecular Weight
115 kDa
Host or Source
Rabbit
Isotype
IgG