BCCIP Polyclonal Antibody

CAT: 0866-RD85197A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD85197A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
Description
This is a BCCIP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BCCIP, TOK-1, TOK1
Gene ID
56647
Swiss Prot
Q9P287
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human BCCIP (NP_510868.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:100-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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