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GNE Polyclonal Antibody

CAT: 0866-RD85187A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD85187A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Description
This is a GNE Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GNE, DMRV, GLCNE, IBM2, NM, Uae1
Gene ID
10020
Swiss Prot
Q9Y223
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human GNE (NP_001121699.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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