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ARHGEF3 Polyclonal Antibody

CAT: 0866-RD85134A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD85134A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a ARHGEF3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ARHGEF3, GEF3, STA3, XPLN
Gene ID
50650
Swiss Prot
Q9NR81
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human ARHGEF3 (NP_062455.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
36 kDa/59 kDa/60 kDa/63 kDa
Observed Molecular Weight
60 kDa
Host or Source
Rabbit
Isotype
IgG

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