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HIRA Polyclonal Antibody

CAT: 0866-RD85116A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD85116A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
Description
This is a HIRA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HIRA, DGCR1, TUP1, TUPLE1
Gene ID
7290
Swiss Prot
P54198
Reactivity
Human
Immunogen
Recombinant fusion protein of human HIRA (NP_003316.3) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:100-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
89 kDa/111 kDa
Observed Molecular Weight
112 kDa
Host or Source
Rabbit
Isotype
IgG

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