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CAD Polyclonal Antibody

CAT: 0866-RD85028A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD85028A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
This is a CAD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CAD, CDG1Z, EIEE50, GATD4
Gene ID
790
Swiss Prot
P27708
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CAD (NP_004332.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
242 kDa
Observed Molecular Weight
243 kDa
Host or Source
Rabbit
Isotype
IgG

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