EXOC2 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

• Description :

  This is a EXOC2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  EXOC2, SEC5, SEC5L1, Sec5p

• Gene ID :

  55770

• Swiss Prot :

  Q96KP1

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human EXOC2 (NP_060773.3) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000 IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  104 kDa

• Observed Molecular Weight :

  108 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG