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NEDD4L Polyclonal Antibody

CAT: 0866-RD84896A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84896A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Description
This is a NEDD4L Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NEDD4L, NEDD4-2, NEDD4.2, PVNH7, RSP5, hNEDD4-2
Gene ID
23327
Swiss Prot
Q96PU5
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human NEDD4L (NP_056092.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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