NEDD4L Polyclonal Antibody

• Background:

  This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Description:

  This is a NEDD4L Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  NEDD4L, NEDD4-2, NEDD4.2, PVNH7, RSP5, hNEDD4-2

• Gene ID:

  23327

• Swiss Prot:

  Q96PU5

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human NEDD4L (NP_056092.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:50-1:200 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG