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MBNL1 Polyclonal Antibody

CAT: 0866-RD84878A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84878A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
Description
This is a MBNL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MBNL1, EXP, MBNL
Gene ID
4154
Swiss Prot
Q9NR56
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MBNL1 (NP_066368.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa/34 kDa/36 kDa/37 kDa/39 kDa/40 kDa/41 kDa
Observed Molecular Weight
42 kDa
Host or Source
Rabbit
Isotype
IgG

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