CFL2 Polyclonal Antibody

• Background:

  This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

• Description:

  This is a CFL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CFL2, NEM7, cofilin-2

• Gene ID:

  1073

• Swiss Prot:

  Q9Y281

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human CFL2 (NP_068733.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  16 kDa/18 kDa

• Observed Molecular Weight:

  18 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG