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EPS15L1 Polyclonal Antibody

CAT: 0866-RD84742A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84742A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR) ; internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.
Description
This is a EPS15L1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
EPS15L1, EPS15R
Gene ID
58513
Swiss Prot
Q9UBC2
Reactivity
Human
Immunogen
Recombinant fusion protein of human EPS15L1 (NP_001245304.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
66 kDa/83 kDa/94 kDa/99 kDa
Observed Molecular Weight
110 kDa
Host or Source
Rabbit
Isotype
IgG

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