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DPM1 Polyclonal Antibody

CAT: 0866-RD84692A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84692A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER) . Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.
Description
This is a DPM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DPM1, CDGIE, MPDS
Gene ID
8813
Swiss Prot
O60762
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human DPM1 (NP_003850.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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