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STAT5A Polyclonal Antibody

CAT: 0866-RD84669A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD84669A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.
Description
This is a STAT5A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MGF, STAT5, STAT5A
Gene ID
6776
Swiss Prot
P42229
Reactivity
Human
Immunogen
Recombinant fusion protein of human STAT5A (NP_003143.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
86 kDa/90 kDa
Observed Molecular Weight
90 kDa
Host or Source
Rabbit
Isotype
IgG

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